Fig. 5

Inference of cell–cell communications by CellChat shows global alterations in signaling pathway-mediated communications between SV-specific cells in SNHL. Circle plots of the interaction numbers and interaction strength between SV-specific cells (A). The arrows indicate the direction of intercellular communication. Comparison of the total number of cell communication interactions and the strength of these interactions in bar chart (B). Changes in incoming and outgoing signaling in SV-specific cells across different datasets (C). Global comparison of the information flow of signaling pathways in SV cells between the SNHL and adult mouse groups (D, E, F)