Fig. 4

Distribution of ribosomal RNA reads in HMGB1 iRIP-seq. A Summary table for the analyzed iRIP-seq reads mapped to the 45S and 5S rDNAs from two IP and Input samples. B Summary table for the iRIP-seq reads mapped to the 5.8S, 18S, and 28S rDNAs. C Bar plot for the iRIP-seq reads mapped to the 5.8S, 18S, and 28S rDNAs. D Reads distribution of the human 28S rRNA. The diagram reflected the abundant binding region of the HMGB1 in 28S rRNA domain II and modification location. E RIP-qPCR validation of HMGB1-bound rRNA