Fig. 9

Schematic diagram showing the changes in the pathogen proliferation and host responses in congenitally infected embryos and larvae. In the larvae infected with N. bombycis, parasite genes related to parasite proliferation and growth were up-regulated, whereas genes related to central carbon metabolism were down-regulated compared to those expressions in embryos. As the infection progresses in embryos and larvae, host responses including immunity and metabolisms varied. Epigenetic modification was likely to participate in the pathogen-host interactions