Table 6 Top 10 in PPI network ranked by MCC algorithm
Rank | Gene name | Description | MCC score | Change |
|---|---|---|---|---|
1 | PTGS2 | Prostaglandin-endoperoxide synthase 2 | 48 | Up |
2 | IL1B | Interleukin 1 beta | 42 | Down |
3 | NOX4 | NADPH oxidase 4 | 38 | Up |
4 | TXNRD1 | Thioredoxin reductase 1 | 36 | Down |
5 | NQO1 | NAD(P)H quinone dehydrogenase 1 | 32 | Down |
6 | CAV1 | Caveolin 1 | 14 | Down |
7 | LCN2 | Lipocalin 2 | 14 | Down |
8 | TXNIP | Thioredoxin interacting protein | 14 | Down |
9 | AKR1C3 | Aldo–keto reductase family 1 member C3 | 12 | Down |
10 | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5 | 12 | Down |