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Fig. 11 | BMC Genomics

Fig. 11

From: Analysis and prediction of interactions between transmembrane and non-transmembrane proteins

Fig. 11

Top 2 subnetwork topologies from POSI calculated by MCODE algorithm. a The first cluster found by MCODE, reflected the recycling effect of the proteins. b The second cluster fund by MCODE reflected a bridge to connect two sub-clusters. Proteins are presented by nodes and the interactions between them are presented by edges. A bigger node indicates a more important protein in the topology of the cluster. The nodes in orange were TMPs while the nodes in green were nonTMPs. Besides, Proteins recorded in the DrugBank were represented by dark orange or darg green nodes separately for TMP or nonTMPs. The number of lines connected to the nodes represented the degree of the node

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