Fig. 1
From: Multi-trait GWAS for diverse ancestries: mapping the knowledge gap
Overview of the study. After harmonization and imputation of GWAS summary statistics, multi-trait GWAS were performed for the four ancestries on hematological and glycemic phenotypes separately. We computed the heritability, genetic correlation and association statistics covariance under the null for each ancestry. An additional trans-ancestry multi-trait GWAS was conducted for hematological traits. Significant hematological associations were further analyzed through functional annotation and by comparing their position and features across ancestries. *For the EAS ancestry, two traits are missing: mean platelet count volume and red blood cell count distribution width