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  1. Parasite-vector interactions are fundamental in the transmission of vector-borne diseases such as leishmaniasis. Leishmania development in the vector sand fly is confined to the digestive tract, where sand fly mi...

    Authors: Anna Dostálová, Jan Votýpka, Amanda J Favreau, Kent D Barbian, Petr Volf, Jesus G Valenzuela and Ryan C Jochim
    Citation: BMC Genomics 2011 12:223
    Content type: Research article Published on:

  2. Saccharomyces cerevisiae and Pichia pastoris are two of the most relevant microbial eukaryotic platforms for the production of recombinant proteins. Their known genome sequences enabled several transcriptomic pro...

    Authors: Kristin Baumann, Laura Dato, Alexandra B Graf, Gianni Frascotti, Martin Dragosits, Danilo Porro, Diethard Mattanovich, Pau Ferrer and Paola Branduardi
    Citation: BMC Genomics 2011 12:218
    Content type: Research article Published on:

  3. Flax (Linum usitatissimum L.) is an important source of oil rich in omega-3 fatty acids, which have proven health benefits and utility as an industrial raw material. Flax seeds also contain lignans which are asso...

    Authors: Raja Ragupathy, Rajkumar Rathinavelu and Sylvie Cloutier
    Citation: BMC Genomics 2011 12:217
    Content type: Research article Published on:

  4. In the presence of drought and other desiccating stresses, plants synthesize and redistribute the phytohormone abscisic acid (ABA). ABA promotes plant water conservation by acting on specialized cells in the l...

    Authors: Rui-Sheng Wang, Sona Pandey, Song Li, Timothy E Gookin, Zhixin Zhao, Réka Albert and Sarah M Assmann
    Citation: BMC Genomics 2011 12:216
    Content type: Research article Published on:

  5. Schistosomiasis remains an important parasitic disease and a major economic problem in many countries. The Schistosoma mansoni genome and predicted proteome sequences were recently published providing the opportu...

    Authors: Luiza F Andrade, Laila A Nahum, Lívia GA Avelar, Larissa L Silva, Adhemar Zerlotini, Jerônimo C Ruiz and Guilherme Oliveira
    Citation: BMC Genomics 2011 12:215
    Content type: Research article Published on:

  6. Due to its overarching role in genome function, sequence-dependent DNA curvature continues to attract great attention. The DNA double helix is not a rigid cylinder, but presents both curvature and flexibility ...

    Authors: Ali Masoudi-Nejad, Sara Movahedi and Ruy Jáuregui
    Citation: BMC Genomics 2011 12:214
    Content type: Research article Published on:

  7. Genome-wide screening in human and mouse cells using RNA interference and open reading frame over-expression libraries is rapidly becoming a viable experimental approach for many research labs. There are a var...

    Authors: Troy Ketela, Lawrence E Heisler, Kevin R Brown, Ron Ammar, Dahlia Kasimer, Anuradha Surendra, Elke Ericson, Kim Blakely, Dina Karamboulas, Andrew M Smith, Tanja Durbic, Anthony Arnoldo, Kahlin Cheung-Ong, Judice LY Koh, Shuba Gopal, Glenn S Cowley…
    Citation: BMC Genomics 2011 12:213
    Content type: Methodology article Published on:

  8. While an increase in bone marrow adiposity is associated with age-related bone disease, the function of bone marrow adipocytes has not been studied. The aim of this study was to characterize and compare the ag...

    Authors: Li-Fen Liu, Wen-Jun Shen, Masami Ueno, Shailja Patel and Fredric B Kraemer
    Citation: BMC Genomics 2011 12:212
    Content type: Research article Published on:

  9. Milkweeds (Asclepias L.) have been extensively investigated in diverse areas of evolutionary biology and ecology; however, there are few genetic resources available to facilitate and compliment these studies. Thi...

    Authors: Shannon CK Straub, Mark Fishbein, Tatyana Livshultz, Zachary Foster, Matthew Parks, Kevin Weitemier, Richard C Cronn and Aaron Liston
    Citation: BMC Genomics 2011 12:211
    Content type: Research article Published on:

  10. Burkholderia rhizoxinica is an intracellular symbiont of the phytopathogenic zygomycete Rhizopus microsporus, the causative agent of rice seedling blight. The endosymbiont produces the antimitotic macrolide rhizo...

    Authors: Gerald Lackner, Nadine Moebius, Laila P Partida-Martinez, Sebastian Boland and Christian Hertweck
    Citation: BMC Genomics 2011 12:210
    Content type: Research article Published on:

  11. Humans and mice with loss of function mutations in GPR54 (KISS1R) or kisspeptin do not progress through puberty, caused by a failure to release GnRH. The transcriptional networks regulated by these proteins in...

    Authors: Leah M Prentice, Xavier d'Anglemont de Tassigny, Steven McKinney, Teresa Ruiz de Algara, Damian Yap, Gulisa Turashvili, Steven Poon, Margaret Sutcliffe, Pat Allard, Angela Burleigh, John Fee, David G Huntsman, William H Colledge and Samuel AJ Aparicio
    Citation: BMC Genomics 2011 12:209
    Content type: Research article Published on:

  12. The existence of a genetic basis for host responses to bacterial intramammary infections has been widely documented, but the underlying mechanisms and the genes are still largely unknown. Previously, two diver...

    Authors: Cécile MD Bonnefont, Mehdi Toufeer, Cécile Caubet, Eliane Foulon, Christian Tasca, Marie-Rose Aurel, Dominique Bergonier, Séverine Boullier, Christèle Robert-Granié, Gilles Foucras and Rachel Rupp
    Citation: BMC Genomics 2011 12:208
    Content type: Research article Published on:

  13. Small bacterial RNAs (sRNAs) have been shown to participate in the regulation of gene expression and have been identified in numerous prokaryotic species. Some of them are involved in the regulation of virulen...

    Authors: David Hot, Stéphanie Slupek, Bérénice Wulbrecht, Anthony D'Hondt, Christine Hubans, Rudy Antoine, Camille Locht and Yves Lemoine
    Citation: BMC Genomics 2011 12:207
    Content type: Research article Published on:

  16. The proximal region of murine Chr 2 has long been known to harbour one or more imprinted genes from classic genetic studies involving reciprocal translocations. No imprinted gene had been identified from this ...

    Authors: Qianwei Wang, Jacqueline Chow, Jenny Hong, Anne Ferguson Smith, Carol Moreno, Peter Seaby, Paul Vrana, Kamelia Miri, Joon Tak, Eu Ddeum Chung, Gabriela Mastromonaco, Isabella Caniggia and Susannah Varmuza
    Citation: BMC Genomics 2011 12:204
    Content type: Research article Published on:

  17. Significant differences in G+C content between different isochore types suggest that the nucleosome positioning patterns in DNA of the isochores should be different as well.

    Authors: Zakharia M Frenkel, Thomas Bettecken and Edward N Trifonov
    Citation: BMC Genomics 2011 12:203
    Content type: Research article Published on:

  18. Next-generation sequencing is providing researchers with a relatively fast and affordable option for developing genomic resources for organisms that are not among the traditional genetic models. Here we presen...

    Authors: Bonnie A Fraser, Cameron J Weadick, Ilana Janowitz, F Helen Rodd and Kimberly A Hughes
    Citation: BMC Genomics 2011 12:202
    Content type: Research article Published on:

  19. Saccharomyces cerevisiae (Baker's yeast) is found in diverse ecological niches and is characterized by high adaptive potential under challenging environments. In spite of recent advances on the study of yeast gen...

    Authors: Laura Carreto, Maria F Eiriz, Inês Domingues, Dorit Schuller, Gabriela R Moura and Manuel AS Santos
    Citation: BMC Genomics 2011 12:201
    Content type: Research article Published on:

  20. The decline noticed in several fertility traits of dairy cattle over the past few decades is of major concern. Understanding of the genomic factors underlying fertility, which could have potential applications...

    Authors: Arun Kommadath, Henri Woelders, Bonne Beerda, Herman A Mulder, Agnes AC de Wit, Roel F Veerkamp, Marinus FW te Pas and Mari A Smits
    Citation: BMC Genomics 2011 12:200
    Content type: Research article Published on:

  21. Alfalfa, [Medicago sativa (L.) sativa], a widely-grown perennial forage has potential for development as a cellulosic ethanol feedstock. However, the genomics of alfalfa, a non-model species, is still in its infa...

    Authors: S Samuel Yang, Zheng Jin Tu, Foo Cheung, Wayne Wenzhong Xu, JoAnn FS Lamb, Hans-Joachim G Jung, Carroll P Vance and John W Gronwald
    Citation: BMC Genomics 2011 12:199
    Content type: Research article Published on:

  23. Infectious laryngotracheitis virus (ILTV) is an alphaherpesvirus that causes acute respiratory disease in chickens worldwide. To date, only one complete genomic sequence of ILTV has been reported. This sequenc...

    Authors: Sang-Won Lee, Philip F Markham, John F Markham, Ivonne Petermann, Amir H Noormohammadi, Glenn F Browning, Nino P Ficorilli, Carol A Hartley and Joanne M Devlin
    Citation: BMC Genomics 2011 12:197
    Content type: Research article Published on:

  24. Nerve growth factor (NGF) is a potent growth factor that plays a key role in neuronal cell differentiation and may also play a role in hematopoietic differentiation. It has been shown that NGF induced synergis...

    Authors: Priyanka Dutta, Alexandra Koch, Bjoern Breyer, Heike Schneider, Oliver Dittrich-Breiholz, Michael Kracht and Teruko Tamura
    Citation: BMC Genomics 2011 12:196
    Content type: Research article Published on:

  25. Mixtures of chemicals present in aquatic environments may elicit toxicity due to additive or synergistic effects among the constituents or, vice versa, the adverse outcome may be reduced by antagonistic intera...

    Authors: Francesco Dondero, Mohamed Banni, Alessandro Negri, Lara Boatti, Alessandro Dagnino and Aldo Viarengo
    Citation: BMC Genomics 2011 12:195
    Content type: Research article Published on:

  27. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is an environmental contaminant that elicits a broad spectrum of toxic effects in a species-specific manner. Current risk assessment practices routinely extrapolate resu...

    Authors: Edward Dere, Andrea W Lee, Lyle D Burgoon and Timothy R Zacharewski
    Citation: BMC Genomics 2011 12:193
    Content type: Research article Published on:

  29. Jatropha curcas L. is an important non-edible oilseed crop with promising future in biodiesel production. However, factors like oil yield, oil composition, toxic compounds in oil cake, pests and diseases limit it...

    Authors: Purushothaman Natarajan and Madasamy Parani
    Citation: BMC Genomics 2011 12:191
    Content type: Research article Published on:

  30. Milling yield and eating quality are two important grain quality traits in rice. To identify the genes involved in these two traits, we performed a deep transcriptional analysis of developing seeds using both ...

    Authors: R C Venu, M V Sreerekha, Kan Nobuta, André Beló, Yuese Ning, Gynheung An, Blake C Meyers and Guo-Liang Wang
    Citation: BMC Genomics 2011 12:190
    Content type: Research article Published on:

  31. Technological advances are progressively increasing the application of genomics to a wider array of economically and ecologically important species. High-density maps enriched for transcribed genes facilitate ...

    Authors: Leandro G Neves, Eva MC Mamani, Acelino C Alfenas, Matias Kirst and Dario Grattapaglia
    Citation: BMC Genomics 2011 12:189
    Content type: Research article Published on:

  32. Common carp is one of the most important aquaculture teleost fish in the world. Common carp and other closely related Cyprinidae species provide over 30% aquaculture production in the world. However, common ca...

    Authors: Peng Xu, Jiongtang Li, Yan Li, Runzi Cui, Jintu Wang, Jian Wang, Yan Zhang, Zixia Zhao and Xiaowen Sun
    Citation: BMC Genomics 2011 12:188
    Content type: Research article Published on:

  33. Staphylococcus aureus is associated with a spectrum of symbiotic relationships with its human host from carriage to sepsis and is frequently associated with nosocomial and community-acquired infections, thus the ...

    Authors: Robert Boissy, Azad Ahmed, Benjamin Janto, Josh Earl, Barry G Hall, Justin S Hogg, Gordon D Pusch, Luisa N Hiller, Evan Powell, Jay Hayes, Susan Yu, Sandeep Kathju, Paul Stoodley, J Christopher Post, Garth D Ehrlich and Fen Z Hu
    Citation: BMC Genomics 2011 12:187
    Content type: Research article Published on:

  34. Functional studies have demonstrated that microRNAs (miRNAs or miRs) play critical roles in a wide spectrum of biological processes including development and disease pathogenesis. To investigate the functional...

    Authors: Tingting Li, Rimao Wu, Yong Zhang and Dahai Zhu
    Citation: BMC Genomics 2011 12:186
    Content type: Research article Published on:

  35. Clostridium botulinum strains can be divided into four physiological groups that are sufficiently diverged to be considered as separate species. Here we present the first complete genome of a C. botulinum strain ...

    Authors: Hanna Skarin, Therese Håfström, Josefina Westerberg and Bo Segerman
    Citation: BMC Genomics 2011 12:185
    Content type: Research article Published on:

  37. MicroRNAs (miRNAs) are important genetic elements that regulate the expression of thousands of human genes. Polymorphisms affecting miRNA biogenesis, dosage and target recognition may represent potentially fun...

    Authors: Malgorzata Marcinkowska, Maciej Szymanski, Wlodzimierz J Krzyzosiak and Piotr Kozlowski
    Citation: BMC Genomics 2011 12:183
    Content type: Research article Published on:

  38. Diet plays a role on the development of the immune system, and polyunsaturated fatty acids can modulate the expression of a variety of genes. Human milk contains conjugated linoleic acid (CLA), a fatty acid th...

    Authors: Elisabet Selga, Francisco J Pérez-Cano, Àngels Franch, Carolina Ramírez-Santana, Montserrat Rivero, Carlos J Ciudad, Cristina Castellote and Véronique Noé
    Citation: BMC Genomics 2011 12:182
    Content type: Research article Published on:

  39. Multiplex experimental assays coupled to computational predictions are being increasingly employed for the simultaneous analysis of many specimens at the genome scale, which quickly generates very large amount...

    Authors: Milos Pjanic, Petar Pjanic, Christoph Schmid, Giovanna Ambrosini, Armelle Gaussin, Genta Plasari, Christian Mazza, Philipp Bucher and Nicolas Mermod
    Citation: BMC Genomics 2011 12:181
    Content type: Research article Published on:

  40. Rainbow trout (Oncorhynchus mykiss) are the most-widely cultivated cold freshwater fish in the world and an important model species for many research areas. Coupling great interest in this species as a research m...

    Authors: Yniv Palti, Carine Genet, Ming-Cheng Luo, Aurélie Charlet, Guangtu Gao, Yuqin Hu, Cecilia Castaño-Sánchez, Kamila Tabet-Canale, Francine Krieg, Jianbo Yao, Roger L Vallejo and Caird E Rexroad III
    Citation: BMC Genomics 2011 12:180
    Content type: Research article Published on:

  41. Approximately half of the mitochondrial genome inherent within 546 individual Atlantic salmon (Salmo salar) derived from across the species' North Atlantic range, was selectively amplified with a novel combinatio...

    Authors: Olafur Fridjonsson, Kristinn Olafsson, Scott Tompsett, Snaedis Bjornsdottir, Sonia Consuegra, David Knox, Carlos Garcia de Leaniz, Steinunn Magnusdottir, Gudbjorg Olafsdottir, Eric Verspoor and Sigridur Hjorleifsdottir
    Citation: BMC Genomics 2011 12:179
    Content type: Methodology article Published on:

  42. Auxin signaling is vital for plant growth and development, and plays important role in apical dominance, tropic response, lateral root formation, vascular differentiation, embryo patterning and shoot elongatio...

    Authors: Hongyan Xing, Ramesh N Pudake, Ganggang Guo, Guofang Xing, Zhaorong Hu, Yirong Zhang, Qixin Sun and Zhongfu Ni
    Citation: BMC Genomics 2011 12:178
    Content type: Research article Published on:

  43. The evolutionary diversification of gene families through gene creation (and loss) is a dynamic process believed to be critical to the evolution of functional novelty. Previous identification of a closely rela...

    Authors: Steve Dorus, Elaine C Wilkin and Timothy L Karr
    Citation: BMC Genomics 2011 12:177
    Content type: Research article Published on:

  44. MicroRNAs (miRNAs) are small non-coding RNAs that can exert multilevel inhibition/repression at a post-transcriptional or protein synthesis level during disease or development. Characterisation of miRNAs in ad...

    Authors: King-Hwa Ling, Peter J Brautigan, Christopher N Hahn, Tasman Daish, John R Rayner, Pike-See Cheah, Joy M Raison, Sandra Piltz, Jeffrey R Mann, Deidre M Mattiske, Paul Q Thomas, David L Adelson and Hamish S Scott
    Citation: BMC Genomics 2011 12:176
    Content type: Research article Published on:

  45. GlnR is an atypical response regulator found in actinomycetes that modulates the transcription of genes in response to changes in nitrogen availability. We applied a global in vivo approach to identify the GlnR r...

    Authors: Steven T Pullan, Govind Chandra, Mervyn J Bibb and Mike Merrick
    Citation: BMC Genomics 2011 12:175
    Content type: Research article Published on:

  46. High density linkage maps are essential for comparative analysis of synteny, fine mapping of quantitative trait loci (QTL), searching for candidate genes and facilitating genome sequence assembly. However, in ...

    Authors: Chun Ming Wang, Zhi Yi Bai, Xiao Ping He, Grace Lin, Jun Hong Xia, Fei Sun, Loong Chueng Lo, Felicia Feng, Ze Yuan Zhu and Gen Hua Yue
    Citation: BMC Genomics 2011 12:174
    Content type: Research article Published on:

  47. Exposure to the toxic metals arsenic and cadmium is associated with detrimental health effects including cancers of various organs. While arsenic and cadmium are well known to cause adverse health effects at h...

    Authors: Margaret Ann Benton, Julia E Rager, Lisa Smeester and Rebecca C Fry
    Citation: BMC Genomics 2011 12:173
    Content type: Research article Published on:

  49. The Ahringer C. elegans RNAi feeding library prepared by cloning genomic DNA fragments has been widely used in genome-wide analysis of gene function. However, the library has not been thoroughly validated by dire...

    Authors: Wubin Qu, Changhong Ren, Yuan Li, Jinping Shi, Jiye Zhang, Xiaolei Wang, Xingyi Hang, Yiming Lu, Dongsheng Zhao and Chenggang Zhang
    Citation: BMC Genomics 2011 12:170
    Content type: Methodology article Published on:

  50. Yersinia enterocolitica strains responsible for mild gastroenteritis in humans are very diverse with respect to their metabolic and virulence properties. Strain W22703 (biotype 2, serotype O:9) was recently ident...

    Authors: Thilo M Fuchs, Katharina Brandt, Mandy Starke and Thomas Rattei
    Citation: BMC Genomics 2011 12:168
    Content type: Research article Published on:

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BMC Genomics

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