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  1. Cryptocaryon irritans is a parasitic ciliate that causes cryptocaryonosis (white spot disease) in marine fish. Diagnosis of cryptocaryonosis often depends on the appearance of white spots on the surface of the fi...

    Authors: Yogeswaran Lokanathan, Adura Mohd-Adnan, Kiew-Lian Wan and Sheila Nathan
    Citation: BMC Genomics 2010 11:76
    Content type: Research article Published on:

  2. Gene regulation at transcript level can provide a good indication of the complex signaling mechanisms underlying physiological and pathological processes. Transcriptomic methods such as microarray and quantita...

    Authors: Lihan Zhou, Qing-En Lim, Guoqiang Wan and Heng-Phon Too
    Citation: BMC Genomics 2010 11:75
    Content type: Research article Published on:

  3. Sothern blotting is a DNA analysis technique that has found widespread application in molecular biology. It has been used for gene discovery and mapping and has diagnostic and forensic applications, including ...

    Authors: Mike DR Croning, David G Fricker, Noboru H Komiyama and Seth GN Grant
    Citation: BMC Genomics 2010 11:74
    Content type: Software Published on:

  4. Glutathione S-transferases (GSTs) are the ubiquitous enzymes that play a key role in cellular detoxification. Although several GSTs have been identified and characterized in various plant species, the knowledg...

    Authors: Mukesh Jain, Challa Ghanashyam and Annapurna Bhattacharjee
    Citation: BMC Genomics 2010 11:73
    Content type: Research article Published on:

  5. Daily and seasonal changes in temperature are challenges that fish within aquaculture settings cannot completely avoid, and are known to elicit complex organismal and cellular stress responses. We conducted a ...

    Authors: Tiago S Hori, A Kurt Gamperl, Luis OB Afonso, Stewart C Johnson, Sophie Hubert, Jennifer Kimball, Sharen Bowman and Matthew L Rise
    Citation: BMC Genomics 2010 11:72
    Content type: Research article Published on:

  7. The prairie vole (Microtus ochrogaster) is a premier animal model for understanding the genetic and neurological basis of social behaviors. Unlike other biomedical models, prairie voles display a rich repertoire ...

    Authors: Lisa A McGraw, Jamie K Davis, Josh J Lowman, Boudewijn FH ten Hallers, Maxim Koriabine, Larry J Young, Pieter J de Jong, M Katharine Rudd and James W Thomas
    Citation: BMC Genomics 2010 11:70
    Content type: Research article Published on:

  8. Plants engineered for abiotic stress tolerance may soon be commercialized. The engineering of these plants typically involves the manipulation of complex multigene networks and may therefore have a greater pot...

    Authors: Ashraf Abdeen, Jaimie Schnell and Brian Miki
    Citation: BMC Genomics 2010 11:69
    Content type: Research article Published on:

  9. Food supply from the ocean is constrained by the shortage of domesticated and selected fish. Development of genomic models of economically important fishes should assist with the removal of this bottleneck. Eu...

    Authors: Heiner Kuhl, Alfred Beck, Grzegorz Wozniak, Adelino VM Canario, Filip AM Volckaert and Richard Reinhardt
    Citation: BMC Genomics 2010 11:68
    Content type: Research article Published on:

  10. Helicobacter canadensis is an emerging human pathogen and zoonotic agent. The genome of H. canadensis was sequenced previously and determined to contain 29 annotated coding regions associated with homopolymeric t...

    Authors: Lori AS Snyder, Nicholas J Loman, James D Linton, Rebecca R Langdon, George M Weinstock, Brendan W Wren and Mark J Pallen
    Citation: BMC Genomics 2010 11:67
    Content type: Research article Published on:

  12. Tungsten carbide (WC) and tungsten carbide cobalt (WC-Co) nanoparticles are of occupational health relevance because of the increasing usage in hard metal industries. Earlier studies showed an enhanced toxic p...

    Authors: Wibke Busch, Dana Kühnel, Kristin Schirmer and Stefan Scholz
    Citation: BMC Genomics 2010 11:65
    Content type: Research article Published on:

  13. Bordetella pertussis is the causative agent of human whooping cough (pertussis) and is particularly severe in infants. Despite worldwide vaccinations, whooping cough remains a public health problem. A significant...

    Authors: Audrey J King, Tamara van Gorkom, Han GJ van der Heide, Abdolreza Advani and Saskia van der Lee
    Citation: BMC Genomics 2010 11:64
    Content type: Research article Published on:

  14. The availability of two genetically very similar cell lines (A and B) derived from the laboratory isolate Entamoeba histolytica HM-1:IMSS, which differ in their virulence properties, provides a powerful tool for ...

    Authors: Laura Biller, Paul H Davis, Manuela Tillack, Jenny Matthiesen, Hannelore Lotter, Samuel L Stanley Jr, Egbert Tannich and Iris Bruchhaus
    Citation: BMC Genomics 2010 11:63
    Content type: Research article Published on:

  15. Copy number variation is an important component of genetic variation in higher eukaryotes. The extent of natural copy number variation in C. elegans is unknown outside of 2 highly divergent wild isolates and the ...

    Authors: Jason S Maydan, Adam Lorch, Mark L Edgley, Stephane Flibotte and Donald G Moerman
    Citation: BMC Genomics 2010 11:62
    Content type: Research article Published on:

  16. Recent studies have demonstrated that non-protein-coding RNAs (npcRNAs/ncRNAs) play important roles during eukaryotic development, species evolution, and in the etiology of disease. Rhesus macaques are the mos...

    Authors: Yong Zhang, Jun Liu, Chunshi Jia, Tingting Li, Rimao Wu, Jie Wang, Ying Chen, Xiaoting Zou, Runsheng Chen, Xiu-Jie Wang and Dahai Zhu
    Citation: BMC Genomics 2010 11:61
    Content type: Research article Published on:

  17. Identical sequences with a minimal length of about 300 base pairs (bp) have been involved in the generation of various meiotic/mitotic genomic rearrangements through non-allelic homologous recombination (NAHR)...

    Authors: Cinthya J Zepeda-Mendoza, Tzitziki Lemus, Omar Yáñez, Delfino García, David Valle-García, Karla F Meza-Sosa, María Gutiérrez-Arcelus, Yamile Márquez-Ortiz, Rocío Domínguez-Vidaña, Claudia Gonzaga-Jauregui, Margarita Flores and Rafael Palacios
    Citation: BMC Genomics 2010 11:60
    Content type: Research article Published on:

  18. Histone acetyltransferase enzymes (HATs) are implicated in regulation of transcription. HATs from different families may overlap in target and substrate specificity.

    Authors: Rebecca L Nugent, Anna Johnsson, Brian Fleharty, Madelaine Gogol, Yongtao Xue-Franzén, Chris Seidel, Anthony PH Wright and Susan L Forsburg
    Citation: BMC Genomics 2010 11:59
    Content type: Research article Published on:

  20. As uricoletic animals, chickens produce cleidoic eggs, which are self-contained bacteria-resistant biological packages for extra-uterine development of the chick embryo. The eggshell constitutes a natural phys...

    Authors: Vincent Jonchère, Sophie Réhault-Godbert, Christelle Hennequet-Antier, Cédric Cabau, Vonick Sibut, Larry A Cogburn, Yves Nys and Joel Gautron
    Citation: BMC Genomics 2010 11:57
    Content type: Research article Published on:

  21. This paper describes an efficient in silico method for detecting tandem gene arrays (TGAs) in fully sequenced and compact genomes such as those of prokaryotes or unicellular eukaryotes. The originality of this me...

    Authors: Laurence Despons, Philippe V Baret, Lionel Frangeul, Véronique Leh Louis, Pascal Durrens and Jean-Luc Souciet
    Citation: BMC Genomics 2010 11:56
    Content type: Methodology article Published on:

  23. Bacterial plant pathogens are very harmful to their host plants, which can cause devastating agricultural losses in the world. With the development of microbial genome sequencing, many strains of phytopathogen...

    Authors: Na Gao, Ling-Ling Chen, Hong-Fang Ji, Wei Wang, Ji-Wei Chang, Bei Gao, Lin Zhang, Shi-Cui Zhang and Hong-Yu Zhang
    Citation: BMC Genomics 2010 11:54
    Content type: Database Published on:

  24. Non-coding RNAs (ncRNAs) play a crucial role in the intricate regulation of bacterial gene expression, allowing bacteria to quickly adapt to changing environments. In the past few years, a growing number of re...

    Authors: Maarten Vercruysse, Maarten Fauvart, Lore Cloots, Kristof Engelen, Inge M Thijs, Kathleen Marchal and Jan Michiels
    Citation: BMC Genomics 2010 11:53
    Content type: Research article Published on:

  25. In eukaryotes, microRNAs (miRNAs) have emerged as critical regulators of gene expression. The Silkworm (Bombyx mori L.) is one of the most suitable lepidopteran insects for studying the molecular aspects of metam...

    Authors: Guru Jagadeeswaran, Yun Zheng, Niranji Sumathipala, Haobo Jiang, Estela L Arrese, Jose L Soulages, Weixiong Zhang and Ramanjulu Sunkar
    Citation: BMC Genomics 2010 11:52
    Content type: Research article Published on:

  26. Saliva of adult female mosquitoes help sugar and blood feeding by providing enzymes and polypeptides that help sugar digestion, control microbial growth and counteract their vertebrate host hemostasis and infl...

    Authors: Eric Calvo, Irma Sanchez-Vargas, Amanda J Favreau, Kent D Barbian, Van M Pham, Kenneth E Olson and José MC Ribeiro
    Citation: BMC Genomics 2010 11:51
    Content type: Research article Published on:

  27. The Affymetrix GeneChip is a widely used gene expression profiling platform. Since the chips were originally designed, the genome databases and gene definitions have been considerably updated. Thus, more accur...

    Authors: Jun Yin, Sarah McLoughlin, Ian B Jeffery, Antonino Glaviano, Breandan Kennedy and Desmond G Higgins
    Citation: BMC Genomics 2010 11:50
    Content type: Research article Published on:

  29. Recently, it has been discovered that the human genome contains many transcription start sites for non-coding RNA. Regulatory regions related to transcription of this non-coding RNAs are poorly studied. Some o...

    Authors: Yulia A Medvedeva, Marina V Fridman, Nina J Oparina, Dmitry B Malko, Ekaterina O Ermakova, Ivan V Kulakovskiy, Andreas Heinzel and Vsevolod J Makeev
    Citation: BMC Genomics 2010 11:48
    Content type: Research article Published on:

  30. The antenno-maxilary complex (AMC) forms the chemosensory system of the Drosophila larva and is involved in gustatory and olfactory perception. We have previously shown that a mutant allele of the homeodomain tra...

    Authors: Laure Guenin, Mahatsangy Raharijaona, Rémi Houlgatte and Fawzia Baba-Aissa
    Citation: BMC Genomics 2010 11:47
    Content type: Research article Published on:

  32. Chemical communication in mammals involves globular lipocalins that protect and transport pheromones during their passage out of the body. Efficient communication via this protein - pheromone complex is essent...

    Authors: Romana Stopková, Zbyněk Zdráhal, Štěpán Ryba, Ondřej Šedo, Martin Šandera and Pavel Stopka
    Citation: BMC Genomics 2010 11:45
    Content type: Research article Published on:

  33. Bacterial repetitive extragenic palindromes (REPs) compose a distinct group of genomic repeats. They usually occur in high abundance (>100 copies/genome) and are often arranged in composite repetitive structur...

    Authors: Jaroslav Nunvar, Tereza Huckova and Irena Licha
    Citation: BMC Genomics 2010 11:44
    Content type: Research article Published on:

  34. Peach fruit undergoes a rapid softening process that involves a number of metabolic changes. Storing fruit at low temperatures has been widely used to extend its postharvest life. However, this leads to undesi...

    Authors: Ricardo Nilo, Carlos Saffie, Kathryn Lilley, Ricardo Baeza-Yates, Verónica Cambiazo, Reinaldo Campos-Vargas, Mauricio González, Lee A Meisel, Julio Retamales, Herman Silva and Ariel Orellana
    Citation: BMC Genomics 2010 11:43
    Content type: Research article Published on:

  35. Little is known about how apicomplexan parasites have evolved to infect different host species and cell types. Theileria annulata and Theileria parva invade and transform bovine leukocytes but each species favour...

    Authors: William Weir, Tülin Karagenç, Margaret Baird, Andy Tait and Brian R Shiels
    Citation: BMC Genomics 2010 11:42
    Content type: Research article Published on:

  36. Chronic myelogenous leukemia (CML) results from the neoplastic transformation of a haematopoietic stem cell. The hallmark genetic abnormality of CML is a chimeric BCR/ABL1 fusion gene resulting from the Philadelp...

    Authors: Elisabeth P Nacheva, Diana Brazma, Anna Virgili, Julie Howard-Reeves, Anastasios Chanalaris, Katya Gancheva, Margarita Apostolova, Mikel Valgañon, Helen Mazzullo and Colin Grace
    Citation: BMC Genomics 2010 11:41
    Content type: Research article Published on:

  38. Excessive fat deposition is one of the largest problems faced by salmon aquaculture industries, leading to production losses due to high volume of adipose tissue offal. In addition, increased lipid accumulatio...

    Authors: Marijana Todorčević, Stanko Škugor, Aleksei Krasnov and Bente Ruyter
    Citation: BMC Genomics 2010 11:39
    Content type: Research article Published on:

  39. The Soybean Consensus Map 4.0 facilitated the anchoring of 95.6% of the soybean whole genome sequence developed by the Joint Genome Institute, Department of Energy, but its marker density was only sufficient t...

    Authors: David L Hyten, Steven B Cannon, Qijian Song, Nathan Weeks, Edward W Fickus, Randy C Shoemaker, James E Specht, Andrew D Farmer, Gregory D May and Perry B Cregan
    Citation: BMC Genomics 2010 11:38
    Content type: Research article Published on:

  40. Synaptotagmin proteins were first identified in nervous tissue, residing in synaptic vesicles. Synaptotagmins were subsequently found to form a large family, some members of which play important roles in calci...

    Authors: Molly Craxton
    Citation: BMC Genomics 2010 11:37
    Content type: Research article Published on:

  41. Lactic acid bacteria (LAB) are a group of gram-positive, lactic acid producing Firmicutes. They have been extensively used in food fermentations, including the production of various dairy products. The proteol...

    Authors: Mengjin Liu, Jumamurat R Bayjanov, Bernadet Renckens, Arjen Nauta and Roland J Siezen
    Citation: BMC Genomics 2010 11:36
    Content type: Research article Published on:

  42. Plasmodium falciparum is the main causative agent of malaria. Of the 5 484 predicted genes of P. falciparum, about 57% do not have sufficient sequence similarity to characterized genes in other species to warrant...

    Authors: Laurent Bréhélin, Isabelle Florent, Olivier Gascuel and Éric Maréchal
    Citation: BMC Genomics 2010 11:35
    Content type: Research article Published on:

  43. Malaria is the most important parasitic disease in the world with approximately two million people dying every year, mostly due to Plasmodium falciparum infection. During its complex life cycle in the Anopheles v...

    Authors: Emmanuel Bischoff and Catherine Vaquero
    Citation: BMC Genomics 2010 11:34
    Content type: Research article Published on:

  44. Recently, a number of high-resolution genome-wide maps of nucleosome locations in S. cerevisiae have been derived experimentally. However, nucleosome positions are determined in vivo by the combined effects of...

    Authors: Jihua Feng, Xianhua Dai, Qian Xiang, Zhiming Dai, Jiang Wang, Yangyang Deng and Caisheng He
    Citation: BMC Genomics 2010 11:33
    Content type: Research article Published on:

  46. The extracellular promastigote and the intracellular amastigote stages alternate in the digenetic life cycle of the trypanosomatid parasite Leishmania. Amastigotes develop inside parasitophorous vacuoles of mamma...

    Authors: Pedro J Alcolea, Ana Alonso, Manuel J Gómez, Alicia Sánchez-Gorostiaga, Mercedes Moreno-Paz, Eduardo González-Pastor, Alfredo Toraño, Víctor Parro and Vicente Larraga
    Citation: BMC Genomics 2010 11:31
    Content type: Research article Published on:

  47. Classically, models of DNA-transcription factor binding sites (TFBSs) have been based on relatively few known instances and have treated them as sites of fixed length using position weight matrices (PWMs). Var...

    Authors: John E Reid, Kenneth J Evans, Nigel Dyer, Lorenz Wernisch and Sascha Ott
    Citation: BMC Genomics 2010 11:30
    Content type: Research article Published on:

  49. Over the past years, the relationship between gene transcription and chromosomal location has been studied in a number of different vertebrate genomes. Regional differences in gene expression have been found i...

    Authors: Haisheng Nie, Richard PMA Crooijmans, John WM Bastiaansen, Hendrik-Jan Megens and Martien AM Groenen
    Citation: BMC Genomics 2010 11:28
    Content type: Research article Published on:

  50. A large amount of experimental data generated by modern high-throughput technologies is available through various public repositories. Our knowledge about molecular interaction networks, functional biological ...

    Authors: Kaustubh Shinde, Mukta Phatak, Freudenberg M Johannes, Jing Chen, Qian Li, Joshi K Vineet, Zhen Hu, Krishnendu Ghosh, Jaroslaw Meller and Mario Medvedovic
    Citation: BMC Genomics 2010 11:27
    Content type: Software Published on:

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BMC Genomics

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