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  1. Phthalate esters like n-butyl benzyl phthalate (BBP) are widely used plasticizers. BBP has shown endocrine-disrupting properties, thus having a potential effect on hormone-sensitive tissues. The aim of this st...

    Authors: Raquel Moral, Richard Wang, Irma H Russo, Daniel A Mailo, Coral A Lamartiniere and Jose Russo
    Citation: BMC Genomics 2007 8:453
    Content type: Research article Published on:

  2. Plasmodium infection has been shown to compromise the fitness of the mosquito vector, reducing its fecundity and longevity. However, from an evolutionary perspective, the impact of Plasmodium infection as a selec...

    Authors: Ruth Aguilar, Suchismita Das, Yuemei Dong and George Dimopoulos
    Citation: BMC Genomics 2007 8:451
    Content type: Research article Published on:

  3. Soluble sugars, which play a central role in plant structure and metabolism, are also involved in the responses to a number of stresses, and act as metabolite signalling molecules that activate specific or hor...

    Authors: Fanny Ramel, Cécile Sulmon, Francisco Cabello-Hurtado, Ludivine Taconnat, Marie-Laure Martin-Magniette, Jean-Pierre Renou, Abdelhak El Amrani, Ivan Couée and Gwenola Gouesbet
    Citation: BMC Genomics 2007 8:450
    Content type: Research article Published on:

  4. In fungi, light is primarily known to influence general morphogenesis and both sexual and asexual sporulation. In order to expand the knowledge on the effect of light in fungi and to determine the role of the ...

    Authors: Andrè Schuster, Christian P Kubicek, Martina A Friedl, Irina S Druzhinina and Monika Schmoll
    Citation: BMC Genomics 2007 8:449
    Content type: Research article Published on:

  5. Populus is one of favorable model plants because of its small genome. Structural genomics of Populus has reached a breakpoint as nucleotides of the entire genome have been determined. Reaching the post genome era...

    Authors: Tokihiko Nanjo, Tetsuya Sakurai, Yasushi Totoki, Atsushi Toyoda, Mitsuru Nishiguchi, Tomoyuki Kado, Tomohiro Igasaki, Norihiro Futamura, Motoaki Seki, Yoshiyuki Sakaki, Kazuo Shinozaki and Kenji Shinohara
    Citation: BMC Genomics 2007 8:448
    Content type: Research article Published on:

  7. Restriction landmark genomic scanning (RLGS) is one of the most successfully applied methods for the identification of aberrant CpG island hypermethylation in cancer, as well as the identification of tissue sp...

    Authors: Dominic J Smiraglia, Ramakrishnan Kazhiyur-Mannar, Christopher C Oakes, Yue-Zhong Wu, Ping Liang, Tahmina Ansari, Jian Su, Laura J Rush, Laura T Smith, Li Yu, Chunhui Liu, Zunyan Dai, Shih-Shih Chen, Shu-Huei Wang, Joseph Costello, Ilya Ioshikhes…
    Citation: BMC Genomics 2007 8:446
    Content type: Methodology article Published on:

  8. This study reports the first collection of validated microRNA genes in the sea squirt, Ciona intestinalis. MicroRNAs are processed from hairpin precursors to ~22 nucleotide RNAs that base pair to target mRNAs and...

    Authors: Trina M Norden-Krichmar, Janette Holtz, Amy E Pasquinelli and Terry Gaasterland
    Citation: BMC Genomics 2007 8:445
    Content type: Research article Published on:

  9. The evolutionary forces that determine the arrangement of synonymous codons within open reading frames and fine tune mRNA translation efficiency are not yet understood. In order to tackle this question we have...

    Authors: Gabriela R Moura, José P Lousado, Miguel Pinheiro, Laura Carreto, Raquel M Silva, José L Oliveira and Manuel AS Santos
    Citation: BMC Genomics 2007 8:444
    Content type: Research article Published on:

  10. Aproximately 5–10% of cases of mental retardation in males are due to copy number variations (CNV) on the X chromosome. Novel technologies, such as array comparative genomic hybridization (aCGH), may help to u...

    Authors: I Madrigal, L Rodríguez-Revenga, L Armengol, E González, B Rodriguez, C Badenas, A Sánchez, F Martínez, M Guitart, I Fernández-Carvajal, JA Arranz, MI Tejada, LA Pérez-Jurado, X Estivill and M Milà
    Citation: BMC Genomics 2007 8:443
    Content type: Research article Published on:

  11. Xp10 and OP1 are phages of Xanthomonas oryzae pv. oryzae (Xoo), the causative agent of bacterial leaf blight in rice plants, which were isolated in 1967 in Taiwan and in 1954 in Japan, respectively. We recently i...

    Authors: Chia-Ni Lee, Rouh-Mei Hu, Teh-Yuan Chow, Juey-Wen Lin, Hui-Yi Chen, Yi-Hsiung Tseng and Shu-Fen Weng
    Citation: BMC Genomics 2007 8:442
    Content type: Research article Published on:

  12. Transcription factors (TFs) regulate gene transcription and play pivotal roles in various biological processes such as development, cell cycle progression, cell differentiation and tumor suppression. Identifying

    Authors: Alison P Lee, Yuchen Yang, Sydney Brenner and Byrappa Venkatesh
    Citation: BMC Genomics 2007 8:441
    Content type: Database Published on:

  13. Previous studies have shown that burn-elicited stress signals alter expression of certain murine endogenous retroviruses (MuERVs) in distant organs of mice. These findings suggest that MuERVs may participate i...

    Authors: Young-Kwan Lee, Alex Chew, Lauren Fitzsimon, Rita Thomas, David Greenhalgh and Kiho Cho
    Citation: BMC Genomics 2007 8:440
    Content type: Research article Published on:

  14. Pancreatic cancer is the 5th leading cause of cancer death in both males and females. In recent years, a wealth of gene and protein expression studies have been published broadening our understanding of pancre...

    Authors: Claude Chelala, Stephan A Hahn, Hannah J Whiteman, Sayka Barry, Deepak Hariharan, Tomasz P Radon, Nicholas R Lemoine and Tatjana Crnogorac-Jurcevic
    Citation: BMC Genomics 2007 8:439
    Content type: Database Published on:

  15. Recovery growth is a phase of rapid growth that is triggered by adequate refeeding of animals following a period of weight loss caused by starvation. In this study, to obtain more information on the system-wid...

    Authors: Pierre-Yves Rescan, Jerome Montfort, Cécile Rallière, Aurélie Le Cam, Diane Esquerré and Karine Hugot
    Citation: BMC Genomics 2007 8:438
    Content type: Research article Published on:

  16. So far very limited knowledge exists on L-arginine catabolism in cyanobacteria, although six major L-arginine-degrading pathways have been described for prokaryotes. Thus, we have performed a bioinformatic ana...

    Authors: Sarah Schriek, Christian Rückert, Dorothee Staiger, Elfriede K Pistorius and Klaus-Peter Michel
    Citation: BMC Genomics 2007 8:437
    Content type: Research article Published on:

  17. Secreted modular calcium binding protein-1 (Smoc-1) belongs to the BM-40 family which has been implicated with tissue remodeling, angiogenesis and bone mineralization. Besides its anticipated role in embryogenesi...

    Authors: Jyoti Srivastava, Sanjay Premi, Sudhir Kumar, Iqbal Parwez and Sher Ali
    Citation: BMC Genomics 2007 8:436
    Content type: Research article Published on:

  18. Superoxide dismutases (SOD) are ubiquitous metalloenzymes that catalyze the disproportion of superoxide to peroxide and molecular oxygen through alternate oxidation and reduction of their metal ions. In genera...

    Authors: Balakrishnan Priya, Jagadeesan Premanandh, Raman T Dhanalakshmi, Thangaraj Seethalakshmi, Lakshmanan Uma, Dharmar Prabaharan and Gopalakrishnan Subramanian
    Citation: BMC Genomics 2007 8:435
    Content type: Research article Published on:

  19. The genomes of the three parasitic protozoa Trypanosoma cruzi, Trypanosoma brucei and Leishmania major are the main subject of this study. These parasites are responsible for devastating human diseases known as C...

    Authors: Rachel Brenchley, Humera Tariq, Helen McElhinney, Balázs Szöőr, Julie Huxley-Jones, Robert Stevens, Keith Matthews and Lydia Tabernero
    Citation: BMC Genomics 2007 8:434
    Content type: Research article Published on:

  20. Clenbuterol, a beta-agonist, can dramatically reduce pig adipose accumulation at high dosages. However, it has been banned in pig production because people who eat pig products treated with clenbuterol can be ...

    Authors: Jin Zhang, Qiang He, Qiu Y Liu, Wei Guo, Xue M Deng, Wei W Zhang, Xiao X Hu and Ning Li
    Citation: BMC Genomics 2007 8:433
    Content type: Research article Published on:

  22. Despite the potential of the endoplasmic reticulum (ER) stress response to accommodate adaptive pathways, its integration with other environmental-induced responses is poorly understood in plants. We have prev...

    Authors: André ST Irsigler, Maximiller DL Costa, Ping Zhang, Pedro AB Reis, Ralph E Dewey, Rebecca S Boston and Elizabeth PB Fontes
    Citation: BMC Genomics 2007 8:431
    Content type: Research article Published on:

  23. Wounds are increasingly important in our aging societies. Pathologies such as diabetes predispose patients to chronic wounds that can cause pain, infection, and amputation. The vacuum assisted closure device s...

    Authors: Vishal Saxena, Dennis Orgill and Isaac Kohane
    Citation: BMC Genomics 2007 8:430
    Content type: Methodology article Published on:

  24. Grape berry development is a dynamic process that involves a complex series of molecular genetic and biochemical changes divided into three major phases. During initial berry growth (Phase I), berry size incre...

    Authors: Laurent G Deluc, Jérôme Grimplet, Matthew D Wheatley, Richard L Tillett, David R Quilici, Craig Osborne, David A Schooley, Karen A Schlauch, John C Cushman and Grant R Cramer
    Citation: BMC Genomics 2007 8:429
    Content type: Research article Published on:

  25. Grapevine (Vitis species) is among the most important fruit crops in terms of cultivated area and economic impact. Despite this relevance, little is known about the transcriptional changes and the regulatory circ...

    Authors: Stefania Pilati, Michele Perazzolli, Andrea Malossini, Alessandro Cestaro, Lorenzo Demattè, Paolo Fontana, Antonio Dal Ri, Roberto Viola, Riccardo Velasco and Claudio Moser
    Citation: BMC Genomics 2007 8:428
    Content type: Research article Published on:

  26. Extraordinary size variation of higher plant nuclear genomes is in large part caused by differences in accumulation of repetitive DNA. This makes repetitive DNA of great interest for studying the molecular mec...

    Authors: Jiří Macas, Pavel Neumann and Alice Navrátilová
    Citation: BMC Genomics 2007 8:427
    Content type: Research article Published on:

  27. The number of sequenced fungal genomes is ever increasing, with about 200 genomes already fully sequenced or in progress. Only a small percentage of those genomes have been comprehensively studied, for example...

    Authors: Cornelia Hedeler, Han Min Wong, Michael J Cornell, Intikhab Alam, Darren M Soanes, Magnus Rattray, Simon J Hubbard, Nicholas J Talbot, Stephen G Oliver and Norman W Paton
    Citation: BMC Genomics 2007 8:426
    Content type: Database Published on:

  29. Single-nucleotide polymorphisms (SNPs) are the most abundant type of DNA sequence polymorphisms. Their higher availability and stability when compared to simple sequence repeats (SSRs) provide enhanced possibi...

    Authors: Diego Lijavetzky, José Antonio Cabezas, Ana Ibáñez, Virginia Rodríguez and José M Martínez-Zapater
    Citation: BMC Genomics 2007 8:424
    Content type: Research article Published on:

  30. The green peach aphid, Myzus persicae (Sulzer), is a world-wide insect pest capable of infesting more than 40 plant families, including many crop species. However, despite the significant damage inflicted by M. p...

    Authors: John S Ramsey, Alex CC Wilson, Martin de Vos, Qi Sun, Cecilia Tamborindeguy, Agnese Winfield, Gaynor Malloch, Dawn M Smith, Brian Fenton, Stewart M Gray and Georg Jander
    Citation: BMC Genomics 2007 8:423
    Content type: Research article Published on:

  31. Several genome duplications have occurred in the evolutionary history of teleost fish. In returning to a stable diploid state, the polyploid genome reorganized, and large portions are lost, while the fish line...

    Authors: Johan G de Boer, Ryosuke Yazawa, William S Davidson and Ben F Koop
    Citation: BMC Genomics 2007 8:422
    Content type: Research article Published on:

  32. Toll-like receptor-2 (TLR2) and Caspase Recruitment Domain 15 (CARD15) are important pattern recognition receptors that play a role in the initiation of the inflammatory and subsequent immune response. They ha...

    Authors: Sameer D Pant, Flavio S Schenkel, Ivan Leyva-Baca, Bhawani S Sharma and Niel A Karrow
    Citation: BMC Genomics 2007 8:421
    Content type: Research article Published on:

  33. Iron-deficiency leads to the induction of genes related to intestinal iron absorption and homeostasis. By analyzing a large GeneChip® dataset from the rat intestine, we identified a large cluster of 228 genes tha...

    Authors: James F Collins and Zihua Hu
    Citation: BMC Genomics 2007 8:420
    Content type: Research article Published on:

  36. Lactation is an important aspect of mammalian biology and, amongst mammals, marsupials show one of the most complex lactation cycles. Marsupials, such as the tammar wallaby (Macropus eugenii) give birth to a rela...

    Authors: Christophe M Lefèvre, Matthew R Digby, Jane C Whitley, Yvan Strahm and Kevin R Nicholas
    Citation: BMC Genomics 2007 8:417
    Content type: Research article Published on:

  37. The enormous amount of sequence data available in the public domain database has been a gold mine for researchers exploring various themes in life sciences, and hence the quality of such data is of serious con...

    Authors: Yi-An Chen, Chang-Chun Lin, Chin-Di Wang, Huan-Bin Wu and Pei-Ing Hwang
    Citation: BMC Genomics 2007 8:416
    Content type: Methodology article Published on:

  38. Differential expression of genes can be regulated on many different levels. Most global studies of gene regulation concentrate on transcript level regulation, and very few global analyses of differential trans...

    Authors: Christian Lange, Alexander Zaigler, Mathias Hammelmann, Jens Twellmeyer, Günter Raddatz, Stephan C Schuster, Dieter Oesterhelt and Jörg Soppa
    Citation: BMC Genomics 2007 8:415
    Content type: Research article Published on:

  39. Several high-throughput technologies can measure in parallel the abundance of many mRNA transcripts within a sample. These include the widely-used microarray as well as the more recently developed methods base...

    Authors: Junfeng Chen, Vikas Agrawal, Magnus Rattray, Marilyn AL West, Dina A St Clair, Richard W Michelmore, Sean J Coughlan and Blake C Meyers
    Citation: BMC Genomics 2007 8:414
    Content type: Research article Published on:

  40. Suicide is an important and potentially preventable consequence of serious mental disorders of unknown etiology. Gene expression profiling technology provides an unbiased approach to identifying candidate gene...

    Authors: Sanghyeon Kim, Kwang-Ho Choi, Ali Fuat Baykiz and Howard K Gershenfeld
    Citation: BMC Genomics 2007 8:413
    Content type: Research article Published on:

  41. Plant hybrid proline-rich proteins (HyPRPs) are putative cell wall proteins consisting, usually, of a repetitive proline-rich (PR) N-terminal domain and a conserved eight-cysteine motif (8 CM) C-terminal domai...

    Authors: Lenka Dvořáková, Fatima Cvrčková and Lukáš Fischer
    Citation: BMC Genomics 2007 8:412
    Content type: Research article Published on:

  42. Ganoderma lucidum has been widely used as a herbal medicine for promoting health and longevity in China and other Asian countries. Polysaccharide extracts from Ganoderma lucidum have been reported to exhibit immu...

    Authors: Kun-Chieh Cheng, Hsuan-Cheng Huang, Jenn-Han Chen, Jia-Wei Hsu, Hsu-Chieh Cheng, Chern-Han Ou, Wen-Bin Yang, Shui-Tein Chen, Chi-Huey Wong and Hsueh-Fen Juan
    Citation: BMC Genomics 2007 8:411
    Content type: Research article Published on:

  43. We are profoundly ignorant about the diversity of viruses that infect the domain Archaea. Less than 100 have been identified and described and very few of these have had their genomic sequences determined. Here w...

    Authors: Eulyn Pagaling, Richard D Haigh, William D Grant, Don A Cowan, Brian E Jones, Yanhe Ma, Antonio Ventosa and Shaun Heaphy
    Citation: BMC Genomics 2007 8:410
    Content type: Research article Published on:

  44. Transposable elements constitute a significant fraction of plant genomes. The PIF/Harbinger superfamily includes DNA transposons (class II elements) carrying terminal inverted repeats and producing a 3 bp target ...

    Authors: Dariusz Grzebelus, Slawomir Lasota, Tomasz Gambin, Gregory Kucherov and Anna Gambin
    Citation: BMC Genomics 2007 8:409
    Content type: Research article Published on:

  45. Sequencing of the genomes of several Drosophila allows for the first precise analyses of how global sequence patterns change among multiple, closely related animal species. A basic question is whether there are c...

    Authors: Miguel Gallach, Vicente Arnau and Ignacio Marín
    Citation: BMC Genomics 2007 8:408
    Content type: Research article Published on:

  46. Schistosoma mansoni is a blood helminth parasite that causes schistosomiasis, a disease that affects 200 million people in the world. Many orthologs of known mammalian genes have been discovered in this parasite ...

    Authors: Thiago M Venancio, Ricardo DeMarco, Giulliana T Almeida, Katia C Oliveira, João C Setubal and Sergio Verjovski-Almeida
    Citation: BMC Genomics 2007 8:407
    Content type: Research article Published on:

  47. Recent experimental and computational studies have provided overwhelming evidence for a plethora of diverse transcripts that are unrelated to protein-coding genes. One subclass consists of those RNAs that requ...

    Authors: Dominic Rose, Jörg Hackermüller, Stefan Washietl, Kristin Reiche, Jana Hertel, Sven Findeiß, Peter F Stadler and Sonja J Prohaska
    Citation: BMC Genomics 2007 8:406
    Content type: Research article Published on:

  48. Boar taint is a major obstacle when using uncastrated male pigs for swine production. One of the main compounds causing this taint is androstenone, a pheromone produced in porcine testis. Here we use microarra...

    Authors: Maren Moe, Theo Meuwissen, Sigbjørn Lien, Christian Bendixen, Xuefei Wang, Lene Nagstrup Conley, Ingunn Berget, Håvard Tajet and Eli Grindflek
    Citation: BMC Genomics 2007 8:405
    Content type: Research article Published on:

  49. Hypertension is a complex disease with many contributory genetic and environmental factors. We aimed to identify common targets for therapy by gene expression profiling of a resistance artery taken from animal...

    Authors: T Hilton Grayson, Stephen J Ohms, Therese D Brackenbury, Kate R Meaney, Kaiman Peng, Yvonne E Pittelkow, Susan R Wilson, Shaun L Sandow and Caryl E Hill
    Citation: BMC Genomics 2007 8:404
    Content type: Research article Published on:

  50. A collection of genetic deficiencies covering over 70% of the Caenorhabditis elegans genome exists, however the application of these valuable biological tools has been limited due to the incomplete correlation be...

    Authors: Martin R Jones, Jason S Maydan, Stephane Flibotte, Donald G Moerman and David L Baillie
    Citation: BMC Genomics 2007 8:402
    Content type: Methodology article Published on:

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BMC Genomics

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