Table 2 Vocabulary and notation for application of G-Networks to Gene Regulatory Networks
Biology | G-Networks | Notation |
|---|---|---|
Gene | Node where customers are stored | i |
Signals/notch in the scale of the gene activity information [19] | Positive/negative customers | |
mRNA expression level | The number of positive customers | xi |
Translation / protein bursting | Arrival rate of positive customers from the outside of the system | \(\lambda _{i}^{+}\) |
Degradation | Arrival rate of negative customers from the outside of the system | \(\lambda _{i}^{-}\) |
Activation / transcription | Transition probabilities of positive customers | \(p_{{ij}}^{+}\) |
Repression | Transition probabilities of negative customers | \(p_{{ij}}^{-}\) |
Signals not influencing the gene activity | Customers that exit the system | di |
Protein-protein interaction | Service rate | μi |