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  1. The most abundant family of insect cuticular proteins, the CPR family, is recognized by the R&R Consensus, a domain of about 64 amino acids that binds to chitin and is present throughout arthropods. Several sp...

    Authors: R Scott Cornman, Toru Togawa, W Augustine Dunn, Ningjia He, Aaron C Emmons and Judith H Willis
    Citation: BMC Genomics 2008 9:22
    Content type: Research article Published on:

  2. Analysis of non-coding sequences in several bacterial genomes brought to the identification of families of repeated sequences, able to fold as secondary structures. These sequences have often been claimed to b...

    Authors: Luca Cozzuto, Mauro Petrillo, Giustina Silvestro, Pier Paolo Di Nocera and Giovanni Paolella
    Citation: BMC Genomics 2008 9:20
    Content type: Research article Published on:

  5. Domestic animal breeding and product quality improvement require the control of reproduction, nutrition, health and welfare in these animals. It is thus necessary to improve our knowledge of the major physiolo...

    Authors: Agnès Bonnet, Eddie Iannuccelli, Karine Hugot, Francis Benne, Maria F Bonaldo, Marcelo B Soares, François Hatey and Gwenola Tosser-Klopp
    Citation: BMC Genomics 2008 9:17
    Content type: Research article Published on:

  7. In the life cycle of Leishmania within the alimentary canal of sand flies the parasites have to survive the hostile environment of blood meal digestion, escape the blood bolus and attach to the midgut epitheli...

    Authors: Ryan C Jochim, Clarissa R Teixeira, Andre Laughinghouse, Jianbing Mu, Fabiano Oliveira, Regis B Gomes, Dia-Eldin Elnaiem and Jesus G Valenzuela
    Citation: BMC Genomics 2008 9:15
    Content type: Research article Published on:

  8. The repeats in toxin (Rtx) are an important pathogenicity factor involved in host cells invasion of Legionella pneumophila and other pathogenic bacteria. Its role in escaping the host immune system and cytotoxic ...

    Authors: Giuseppe D'Auria, Núria Jiménez, Francesc Peris-Bondia, Carmen Pelaz, Amparo Latorre and Andrés Moya
    Citation: BMC Genomics 2008 9:14
    Content type: Research article Published on:

  10. Germline genetic variation is associated with the differential expression of many human genes. The phenotypic effects of this type of variation may be important when considering susceptibility to common geneti...

    Authors: Xavier Solé, Pilar Hernández, Miguel López de Heredia, Lluís Armengol, Benjamín Rodríguez-Santiago, Laia Gómez, Christopher A Maxwell, Fernando Aguiló, Enric Condom, Jesús Abril, Luis Pérez-Jurado, Xavier Estivill, Virginia Nunes, Gabriel Capellá, Stephen B Gruber, Víctor Moreno…
    Citation: BMC Genomics 2008 9:12
    Content type: Research article Published on:

  11. Mitochondrial (mt) genomes represent a rich source of molecular markers for a range of applications, including population genetics, systematics, epidemiology and ecology. In the present study, we used 454 tech...

    Authors: Aaron R Jex, Min Hu, D Timothy J Littlewood, Andrea Waeschenbach and Robin B Gasser
    Citation: BMC Genomics 2008 9:11
    Content type: Research article Published on:

  12. Halibuts are commercially important flatfish species confined to the North Pacific and North Atlantic Oceans. We have determined the complete mitochondrial genome sequences of four specimens each of Atlantic h...

    Authors: Kenneth A Mjelle, Bård O Karlsen, Tor E Jørgensen, Truls Moum and Steinar D Johansen
    Citation: BMC Genomics 2008 9:10
    Content type: Research article Published on:

  13. Rapid progress in the field of gene expression-based molecular network integration has generated strong demand on enhancing the sensitivity and data accuracy of experimental systems. To meet the need, a high-t...

    Authors: Guohong Hu, Qifeng Yang, Xiangfeng Cui, Gang Yue, Marco A Azaro, Hui-Yun Wang and Honghua Li
    Citation: BMC Genomics 2008 9:9
    Content type: Methodology article Published on:

  16. Physarum polycephalum, an acellular plasmodial species belongs to the amoebozoa, a major branch in eukaryote evolution. Its complex life cycle and rich cell biology is reflected in more than 2500 publications on ...

    Authors: Gernot Glöckner, Georg Golderer, Gabriele Werner-Felmayer, Sonja Meyer and Wolfgang Marwan
    Citation: BMC Genomics 2008 9:6
    Content type: Research article Published on:

  17. Most emerging health threats are of zoonotic origin. For the overwhelming majority, their causative agents are RNA viruses which include but are not limited to HIV, Influenza, SARS, Ebola, Dengue, and Hantavir...

    Authors: Appolinaire Djikeng, Rebecca Halpin, Ryan Kuzmickas, Jay DePasse, Jeremy Feldblyum, Naomi Sengamalay, Claudio Afonso, Xinsheng Zhang, Norman G Anderson, Elodie Ghedin and David J Spiro
    Citation: BMC Genomics 2008 9:5
    Content type: Methodology article Published on:

  18. Gene clustering plays an important role in the organization of the bacterial chromosome and several mechanisms have been proposed to explain its extent. However, the controversies raised about the validity of ...

    Authors: Gang Fang, Eduardo PC Rocha and Antoine Danchin
    Citation: BMC Genomics 2008 9:4
    Content type: Research article Published on:

  21. Intracellular Wolbachia bacteria are obligate, maternally-inherited, endosymbionts found frequently in insects and other invertebrates. The success of Wolbachia can be attributed in part to an ability to alter ho...

    Authors: Zhiyong Xi, Laurent Gavotte, Yan Xie and Stephen L Dobson
    Citation: BMC Genomics 2008 9:1
    Content type: Research article Published on:

  22. MicroRNAs (miRNAs) are small RNAs (sRNA) ~21 nucleotides in length that negatively control gene expression by cleaving or inhibiting the translation of target gene transcripts. miRNAs have been extensively ana...

    Authors: Abdelali Barakat, Phillip K Wall, Scott DiLoreto, Claude W dePamphilis and John E Carlson
    Citation: BMC Genomics 2007 8:481
    Content type: Research article Published on:

  23. Macaca fascicularis (cynomolgus or longtail macaques) is the most commonly used non-human primate in biomedical research. Little is known about the genomic variation in cynomolgus macaques or how the sequence var...

    Authors: Summer L Street, Randall C Kyes, Richard Grant and Betsy Ferguson
    Citation: BMC Genomics 2007 8:480
    Content type: Research article Published on:

  24. MacroH2A1 is a histone variant that is closely associated with the repressed regions of chromosomes. A recent study revealed that this histone variant is highly enriched in the inactive alleles of Imprinting C...

    Authors: Jung Ha Choo, Jeong Do Kim and Joomyeong Kim
    Citation: BMC Genomics 2007 8:479
    Content type: Research article Published on:

  25. Much of our current knowledge of the molecular expression profile of human embryonic stem cells (hESCs) is based on transcriptional approaches. These analyses are only partly predictive of protein expression h...

    Authors: Thomas C Schulz, Anna Maria Swistowska, Ying Liu, Andrzej Swistowski, Gail Palmarini, Sandii N Brimble, Eric Sherrer, Allan J Robins, Mahendra S Rao and Xianmin Zeng
    Citation: BMC Genomics 2007 8:478
    Content type: Research article Published on:

  26. Genomic research tools such as microarrays are proving to be important resources to study the complex regulation of genes that respond to environmental perturbations. A first generation cDNA microarray was dev...

    Authors: Joseph R Shaw, John K Colbourne, Jennifer C Davey, Stephen P Glaholt, Thomas H Hampton, Celia Y Chen, Carol L Folt and Joshua W Hamilton
    Citation: BMC Genomics 2007 8:477
    Content type: Research article Published on:

  27. Iron is one of fourteen mineral elements required for proper plant growth and development of soybean (Glycine max L. Merr.). Soybeans grown on calcareous soils, which are prevalent in the upper Midwest of the Uni...

    Authors: Jamie A O'Rourke, Dirk V Charlson, Delkin O Gonzalez, Lila O Vodkin, Michelle A Graham, Silvia R Cianzio, Michael A Grusak and Randy C Shoemaker
    Citation: BMC Genomics 2007 8:476
    Content type: Research article Published on:

  28. Ice, snow and temperatures of -14°C are conditions which most animals would find difficult, if not impossible, to survive in. However this exactly describes the Arctic winter, and the Arctic springtail Onychiurus...

    Authors: Melody S Clark, Michael AS Thorne, Jelena Purać, Gordana Grubor-Lajšić, Michael Kube, Richard Reinhardt and M Roger Worland
    Citation: BMC Genomics 2007 8:475
    Content type: Research article Published on:

  29. The xylem-inhabiting bacterium Xylella fastidiosa (Xf) is the causal agent of Pierce's disease (PD) in vineyards and citrus variegated chlorosis (CVC) in orange trees. Both of these economically-devastating disea...

    Authors: Vivian S da Silva, Cláudio S Shida, Fabiana B Rodrigues, Diógenes CD Ribeiro, Alessandra A de Souza, Helvécio D Coletta-Filho, Marcos A Machado, Luiz R Nunes and Regina Costa de Oliveira
    Citation: BMC Genomics 2007 8:474
    Content type: Research article Published on:

  30. The corn smut fungus Ustilago maydis is a well-established model system for molecular phytopathology. In addition, it recently became evident that U. maydis and humans share proteins and cellular processes that a...

    Authors: Martin Münsterkötter and Gero Steinberg
    Citation: BMC Genomics 2007 8:473
    Content type: Research article Published on:

  31. NOD2 is an innate immune receptor for the bacterial cell wall component muramyl-dipeptide. Mutations in the leucine-rich repeat region of NOD2, which lead to an impaired recognition of muramyl-dipeptide, have ...

    Authors: Philip Rosenstiel, Klaus Huse, Andre Franke, Jochen Hampe, Kathrin Reichwald, Cornelia Platzer, Roland G Roberts, Christopher G Mathew, Matthias Platzer and Stefan Schreiber
    Citation: BMC Genomics 2007 8:472
    Content type: Research article Published on:

  32. The Oomycete genus Aphanomyces comprises devastating plant and animal pathogens. However, little is known about the molecular mechanisms underlying pathogenicity of Aphanomyces species. In this study, we report o...

    Authors: Mohammed-Amine Madoui, Elodie Gaulin, Catherine Mathé, Hélène San Clemente, Arnaud Couloux, Patrick Wincker and Bernard Dumas
    Citation: BMC Genomics 2007 8:471
    Content type: Database Published on:

  34. Recent studies using high-throughput methods have revealed that transposable elements (TEs) are a comprehensive target for DNA methylation. However, the relationship between TEs and their genomic environment r...

    Authors: Miwako Takata, Akihiro Kiyohara, Atsuko Takasu, Yuji Kishima, Hisako Ohtsubo and Yoshio Sano
    Citation: BMC Genomics 2007 8:469
    Content type: Research article Published on:

  35. The soybean (Glycine max) cotyledon is a specialized tissue whose main function is to serve as a nutrient reserve that supplies the needs of the young plant throughout seedling development. During this process th...

    Authors: Delkin O Gonzalez and Lila O Vodkin
    Citation: BMC Genomics 2007 8:468
    Content type: Research article Published on:

  36. Small untranslated RNAs (sRNAs) seem to be far more abundant than previously believed. The number of sRNAs confirmed in E. coli through various approaches is above 70, with several hundred more sRNA candidate gen...

    Authors: Vincent M Ulvé, Emeric W Sevin, Angélique Chéron and Frédérique Barloy-Hubler
    Citation: BMC Genomics 2007 8:467
    Content type: Research article Published on:

  37. The invasion of Anopheles salivary glands by Plasmodium sporozoites is an essential step for transmission of the parasite to the vertebrate host. Salivary gland sporozoites undergo a developmental programme to ex...

    Authors: Isabelle Rosinski-Chupin, Thomas Chertemps, Bertrand Boisson, Sylvie Perrot, Emmanuel Bischoff, Jérôme Briolay, Pierre Couble, Robert Ménard, Paul Brey and Patricia Baldacci
    Citation: BMC Genomics 2007 8:466
    Content type: Research article Published on:

  38. Tomato has excellent genetic and genomic resources including a broad set of Expressed Sequence Tag (EST) data and high-density genetic maps. In addition, emerging physical maps and bacterial artificial clone s...

    Authors: Allen Van Deynze, Kevin Stoffel, C Robin Buell, Alexander Kozik, Jia Liu, Esther van der Knaap and David Francis
    Citation: BMC Genomics 2007 8:465
    Content type: Research article Published on:

  39. Sexual reproduction is a core biological function that is conserved throughout eukaryotic evolution, yet breeding systems are extremely variable. Genome-wide comparative studies can be effectively used to iden...

    Authors: Brian D Eads, John K Colbourne, Elizabeth Bohuski and Justen Andrews
    Citation: BMC Genomics 2007 8:464
    Content type: Research article Published on:

  40. Armigeres subalbatus is a natural vector of the filarial worm Brugia pahangi, but it rapidly and proficiently kills Brugia malayi microfilariae by melanotic encapsulation. Because B. malayi and B. pahangi are mor...

    Authors: Matthew T Aliota, Jeremy F Fuchs, George F Mayhew, Cheng-Chen Chen and Bruce M Christensen
    Citation: BMC Genomics 2007 8:463
    Content type: Research article Published on:

  41. The mosquito, Armigeres subalbatus, mounts a distinctively robust innate immune response when infected with the nematode Brugia malayi, a causative agent of lymphatic filariasis. In order to mine the transcriptom...

    Authors: George F Mayhew, Lyric C Bartholomay, Hang-Yen Kou, Thomas A Rocheleau, Jeremy F Fuchs, Matthew T Aliota, I-Yu Tsao, Chiung-Yen Huang, Tze-Tze Liu, Kwang-Jen Hsiao, Shih-Feng Tsai, Ueng-Cheng Yang, Nicole T Perna, Wen-Long Cho, Bruce M Christensen and Cheng-Chen Chen
    Citation: BMC Genomics 2007 8:462
    Content type: Research article Published on:

  42. The biomedical literature is a rich source of associative information but too vast for complete manual review. We have developed an automated method of literature interrogation called "Literature Lab" that ide...

    Authors: Phillip G Febbo, Mike G Mulligan, David A Slonina, Kimberly Stegmaier, Dolores Di Vizio, Paul R Martinez, Massimo Loda and Stephen C Taylor
    Citation: BMC Genomics 2007 8:461
    Content type: Software Published on:

  43. Gene fusion detection – also known as the 'Rosetta Stone' method – involves the identification of fused composite genes in a set of reference genomes, which indicates potential interactions between its un-fuse...

    Authors: Atanas Kamburov, Leon Goldovsky, Shiri Freilich, Aliki Kapazoglou, Victor Kunin, Anton J Enright, Athanasios Tsaftaris and Christos A Ouzounis
    Citation: BMC Genomics 2007 8:460
    Content type: Research article Published on:

  45. Craniosynostosis, the premature fusion of calvarial sutures, is a common craniofacial abnormality. Causative mutations in more than 10 genes have been identified, involving fibroblast growth factor, transformi...

    Authors: Anna K Coussens, Christopher R Wilkinson, Ian P Hughes, C Phillip Morris, Angela van Daal, Peter J Anderson and Barry C Powell
    Citation: BMC Genomics 2007 8:458
    Content type: Research article Published on:

  46. The recent advances in human genetics have recently provided new insights into phenotypic variation and genome variability. Current forensic DNA techniques involve the search for genetic similarities and diffe...

    Authors: Emiliano Giardina, Ilenia Pietrangeli, Claudia Martone, Paola Asili, Irene Predazzi, Patrizio Marsala, Luciano Gabriele, Claudio Pipolo, Omero Ricci, Gianluca Solla, Luca Sineo, Aldo Spinella and Giuseppe Novelli
    Citation: BMC Genomics 2007 8:457
    Content type: Research article Published on:

  48. The signal transducer and activator of transcription 3 (STAT3) mediates gene expression in response to numerous growth factors and cytokines, playing an important role in many cellular processes. To better und...

    Authors: Yan Xu, Machiko Ikegami, Yanhua Wang, Yohei Matsuzaki and Jeffrey A Whitsett
    Citation: BMC Genomics 2007 8:455
    Content type: Research article Published on:

  49. Wild-type laboratory strains of model organisms are typically kept in isolation for many years, with the action of genetic drift and selection on mutational variation causing lineages to diverge with time. Nat...

    Authors: Dean A Baker, Lisa A Meadows, Jing Wang, Julian AT Dow and Steven Russell
    Citation: BMC Genomics 2007 8:454
    Content type: Research article Published on:

  50. Microarray analyses allow the identification and assessment of molecular signatures in whole tissues undergoing pathological processes. To better understand cerebral malaria pathogenesis, we investigated intra...

    Authors: Nicolas F Delahaye, Nicolas Coltel, Denis Puthier, Mathieu Barbier, Philippe Benech, Florence Joly, Fuad A Iraqi, Georges E Grau, Catherine Nguyen and Pascal Rihet
    Citation: BMC Genomics 2007 8:452
    Content type: Research article Published on:

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BMC Genomics

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